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Wednesday, September 24, 2014

Yohimbe (Pausinystalia yohimbe)

Yohimbe (The Herbal Viagra)

Scientific Name(s): Pausinystalia yohimbe
Common Name(s): Aphrodien, Aphrodyne, johimbi, Yocon, yohimbe, yohimbehe, yohimbine.

The bark of the yohimbe tree is used as a remedy for erectile dysfunction (ED). Yohimbine has been used primarily in the treatment of sexual dysfunction, weight (body fat) loss, and xerostomia (dry mouth).
Yohimbe bark extract should not be confused with yohimbine hydrochloride as Yohimbine Hydrochloride has been available by prescription in the U.S. as a treatment for impotence and cannot be used as evidence for effectiveness of the dietary supplement. Yohimbe contains a chemical called yohimbine which can increase blood flow and nerve impulses to the penis or vagina. It also helps counteract the sexual side effects of certain medications used for depression. Yohimbine refers to the active chemical found not only in yohimbe but also in Indian snakewood, periwinkle, quebracho, and niando.
The bark of this tree is considered the best natural treatment for reversing sexual dysfunction but at the cost of several side effects. It is Called "herbal viagra". Apart from men Yohimbe is also effective in women. This herb increases blood flow to the genitals of both males and females giving women an enhanced sensation and engorgement of genital organs. Yohimbine, can improve sexual problems associated with medications used for depression (Sexual problems caused by selective-serotonin reuptake inhibitors or SSRIs). In traditional African medicine system Yohimbe is used to treat Sexual excitement, Exhaustion, Chest pain, Diabetic complications, Depression. Yohimbe is also used as a muscle building natural version of anabolic steroids.
Associated Side effacts:
When taken by mouth in typical doses, yohimbe and the ingredient yohimbine can cause stomach upset, excitation, tremor, sleep problems, anxiety or agitation, high blood pressure, a racing heartbeat, dizziness, stomach problems, drooling, sinus pain, irritability, headache, frequent urination, bloating, rash, nausea, and vomiting.
Taking high doses can also cause other severe problems, including difficulty breathing, paralysis, very low blood pressure, heart problems, and death. After taking a one-day dose of yohimbine, one person reported an allergic reaction involving fever; chills; listlessness; itchy, scaly skin; progressive kidney failure; and symptoms that looked like the auto-immune disease called lupus.

Special precautions & warnings: 

Pregnancy or breast-feeding, Schizophrenia, Prostate problems,, Post-traumatic stress disorder (PTSD), Liver disease, Kidney disease, High blood pressure or low blood pressure, Chest pain or heart disease, Anxiety, Depression, Diabetes.

Do not take this combination
Medications for depression (MAOIs), Clonidine (Catapres), Guanabenz (Wytensin), Medications for depression (Tricyclic antidepressants), Medications for high blood pressure (Antihypertensive drugs), Naloxone (Narcan), Phenothiazines, Stimulant drugs.
Caffeine-containing herbs and supplements, Ephedra, Foods that can narrow the blood vessels, Foods that contain tyramine. 
Adverse Reactions:
Clinical trials report few serious adverse reactions. There are case reports of rash, lupus-like syndrome, bronchospasm, severe hypotension, dysrhythmia, heart failure, and death. Increased anxiety, irritability, and excitability have also been reported. Animal studies suggest yohimbine may increase motor activity and seizures at higher dosages. Yohimbe may precipitate psychoses in predisposed individuals. One should not use yohimbe if you have kidney, liver, heart, or psychiatric problems. Yohimbe products may interact with other supplements or medications you may be talking.
This drug should not be used in the presence of renal or hepatic function impairment.
Do not use during pregnancy or lactation.
Children should not take yohimbe.

It is strongly recommended to keep the dose low to prevent the yohimbe side effects and consult with your doctor/expert before administration.

Monday, September 22, 2014


Sexual dysfunction is a serious medical and social symptom that occurs in 10-52% of men and 25-63% of women. Erectile Dysfunction, the main reason of male impotence, is considered as one of the most important public health problems, since it affects a great percentage of men. Erectile Dysfunction is defined as the consistent inability to obtain or maintain an erection for satisfactory sexual relations. An estimated 20-30 million men suffer from some degree of sexual dysfunction.

1.       Sexual dysfunction occurs commonly in middle-aged and older men.
2.       Impotence occurs in 50% of men with diabetes mellitus.
3.       Atherosclerosis is the cause of approximately 40% of Erectile Dysfunction in men older than 50 years.
4.       Among the most commonly recognized conditions associated are high blood pressure, lipid problems (cholesterol, triglycerides), diabetes, and cigarette smoking.
5.       Endocrine disorders like low testosterone and thyroid problems also contributes to Erectile Dysfunction.
6.       Pelvic trauma, pelvic surgery (major prostate, bladder, and bowel operations) and pelvic radiation therapies are also connected with Erectile Dysfunction.
7.       Direct trauma to the perineum can cause vascular problems in the penis and lead to Erectile Dysfunction that may be treatable by penile artery bypass surgery.
8.       Sexual dysfunction is also caused by various factors such as psychological disorders like anxiety, depression, stress, fear of sex, neurological disorders, stroke, cerebral trauma and Parkinson's disease, penile diseases like phinosis, peyroniesetc.
9.       Other organic causes include chronic renal failure, hepatic failure, multiple sclerosis, Alzheimer's disease, sleep apnea and chronic obstructive pulmonary disease.
10.  Chronic alcohol abuse and cigarette smoking also adversely affect sexual potency.
11.  Decrease in hormone level with age, systemic diseases like cancer also influences sexual ability.
12.  Erectile Dysfunction is also associated with some therapeutic agents like antihypertensives, antipsychotics, antidepressants, and drugs for diabetes mellitus.


An aphrodisiac is an agent (food or drug) that arouses sexual desire. The hunt for natural supplement from medicinal plants is being intensified mainly because of its fewer side effects. In this review, we have mentioned the pharmacologically tested (either in man or animal or in both) aphrodisiac plants, which have claimed for its uses.

An aphrodisiac is defined as any food or drug that arouses the sexual instinct, induces veneral desire and increases pleasure and performance. A lot of natural substances have historically been known as aphrodisiacs in Africa and Europe, like yohimbine and the mandrake plant, as well as ground rhinoceros horn in the Chinese culture and “Spanish fly” which is actually toxic. Even in today's culture, there are certain foods that are used as aphrodisiacs, including strawberries and raw oysters. Chocolate, coffee, and honey are also believed to have aphrodisiac potential. Although these natural items are claimed as aphrodisiacs, there is no or little scientific confirmation supporting those assertions.
Aphrodisiacs can be classified by their mode of action into three types: Those that increase libido, potency, or sexual pleasure. Various substances of animal and plant origin have been used in folk medicines of different cultures to energize, vitalize and improve sexual function, and physical performance in men, out of these very few have been identified pharmacologically.
·        For increasing libido, ambrein, a major constituent of Ambra grisea, is used in Arab countries. It contains a tricyclic triterpene alcohol which increases the concentration of several anterior pituitary hormones and serum testosterone.
·        Bufo toad skin and glands contain bufotenine (and other bufadienolides), a hallucinogenic congener of serotonin. It is the active ingredient in West Indian “love stone” and the Chinese medication chan su.
·        In traditional Chinese medicine, Panax ginseng is used as a sex stimulant. It works as an antioxidant by enhancing nitric oxide (NO) synthesis in the endothelium of corpora cavernosa (CC); ginsenosides also cause transmural nerve stimulation-activated relaxation associated with increased tissue cyclic guanosine monophosphate.
·        For increasing sexual pleasure, cantharidin (“Spanish fly”) from blister beetles, which have been used for millennia as a sexual stimulant.
According to Ayurveda, some herbs have been traditionally used as Vajikaran Rasayana herbs because of their putative positive influence on sexual performance in humans.